Lisa Pisano, the first person to receive a mechanical heart pump as well as a gene-edited pig kidney, died Sunday, according to NYU Langone Health, where she had the surgery. <\/p>\n
Pisano received the transplant on April 12, but the organ failed due to limited blood flow and was removed May 29. <\/p>\n
Her case was the first reported organ transplant in a person with a mechanical heart pump, NYU Langone said, the second known transplant of a gene-edited pig kidney into a living recipient and the first transplanted along with the animal\u2019s thymus gland. <\/p>\n
Pisano was brave and altruistic, Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, said in a statement Tuesday. <\/p>\n
She had said during a news conference after the procedure that even if the organ transplant didn\u2019t work for her, it might for the next person. <\/p>\n
\u201cAt least somebody is going to benefit from it,\u201d she said. <\/p>\n
Montgomery said Tuesday that \u201cLisa\u2019s contributions to medicine, surgery, and xenotransplantation cannot be overstated. \u2026 Lisa helped bring us closer to realizing a future where someone does not have to die for another person to live.\u201d <\/p>\n
Every eight minutes, another person is added to the transplant waiting list, and 17 people from this list die each day waiting for an organ, according to the Organ Procurement and Transplantation Network. Xenotransplantation, which involves using organs from other species, is a potential solution to the shortage of available donor organs, experts say. <\/p>\n
Doctors in the US perform xenotransplants in rare cases, with permission from the US Food and Drug Administration. For Pisano, the permission came through the agency\u2019s expanded-access or \u201ccompassionate use\u201d policy, which allows terminally ill patients who have no other treatment options to access experimental medical products. <\/p>\n
Due to Pisano\u2019s heart failure and end-stage kidney disease that required routine dialysis, she couldn\u2019t have a standard transplant, NYU Langone said in a news release. <\/p>\n
Before the xenotransplant, Pisano said, she had \u201ctried everything else\u201d and, with the surgery, was hoping to spend time with her grandkids and play with them. <\/p>\n
The pig kidney she received was genetically altered to evade human antibodies, which typically detect and attack foreign organs. The pig\u2019s thymus gland, which plays a role in immunity, was placed beneath the pig kidney\u2019s cover to further help Pisano\u2019s body accept the organ. <\/p>\n
However, the kidney was removed in May after it was determined that it was \u201cno longer contributing enough to justify continuing the immunosuppression regimen,\u201d Montgomery said at the time. <\/p>\n
Pisano\u2019s \u201cbravery gave hope to thousands of people living with end-stage kidney or heart failure who could soon benefit from an alternative supply of organs,\u201d he said in Tuesday\u2019s statement. <\/p>\n
\u201cHer legacy as a pioneer will live on and she will forever be remembered for her courage and good nature.\u201d <\/p>\n<\/p>\n
Lisa Pisano, the first person to receive a mechanical heart pump as well as a gene-edited pig kidney, died Sunday, according to NYU Langone Health, where she had the surgery. Pisano received the transplant on April 12, but the organ failed due to limited blood flow and was removed May 29. Her case was the first reported organ …<\/p>\n","protected":false},"author":1,"featured_media":1184,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"loftocean_post_primary_category":0,"loftocean_post_format_gallery":"","loftocean_post_format_gallery_ids":"","loftocean_post_format_gallery_urls":"","loftocean_post_format_video_id":0,"loftocean_post_format_video_url":"","loftocean_post_format_video_type":"","loftocean_post_format_video":"","loftocean_post_format_audio_type":"","loftocean_post_format_audio_url":"","loftocean_post_format_audio_id":0,"loftocean_post_format_audio":"","loftocean-featured-post":"","loftocean-like-count":0,"loftocean-view-count":560,"tinysalt_single_post_intro_label":"","tinysalt_single_post_intro_description":"","tinysalt_hide_post_featured_image":"","tinysalt_post_featured_media_position":"","tinysalt_single_site_header_source":"","tinysalt_single_custom_site_header":"0","tinysalt_single_custom_sticky_site_header":"0","tinysalt_single_custom_sticky_site_header_style":"sticky-scroll-up","tinysalt_single_site_footer_source":"","tinysalt_single_custom_site_footer":"0","footnotes":""},"categories":[35],"tags":[],"class_list":["post-1183","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-news"],"_links":{"self":[{"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/posts\/1183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/comments?post=1183"}],"version-history":[{"count":0,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/posts\/1183\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/media\/1184"}],"wp:attachment":[{"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/media?parent=1183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/categories?post=1183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/retirednurseblog.com\/index.php\/wp-json\/wp\/v2\/tags?post=1183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}